Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB08895"

Predicate	Value (sorted: default)
rdfs:label	"Tofacitinib"
rdf:type	drugbank:drugs
drugbank:description	"Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signaling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and the treatment of psoriasis and ulcerative colitis. Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz. "
drugbank:interactsWith	drug:Etanercept drug:Anakinra drug:Adalimumab drug:Infliximab drug:Trastuzumab drug:Rituximab drug:Cyclosporine drug:Natalizumab drug:Fluconazole drug:Phenytoin drug:Pimecrolimus drug:Clozapine drug:Mifepristone drug:Tacrolimus drug:Rifampicin drug:Leflunomide drug:Abatacept drug:Deferasirox drug:Roflumilast drug:Homoharringtonine drug:ado-trastuzumab emtansine drug:Canakinumab drug:Sitaxentan drug:Tocilizumab drug:Denosumab drug:golimumab drug:Ivacaftor drug:Certolizumab pegol
owl:sameAs	drug:Etanercept drug:Anakinra drug:Adalimumab drug:Infliximab drug:Trastuzumab drug:Rituximab drug:Cyclosporine drug:Natalizumab drug:Fluconazole drug:Phenytoin drug:Pimecrolimus drug:Clozapine drug:Mifepristone drug:Tacrolimus drug:Rifampicin drug:Leflunomide drug:Abatacept drug:Deferasirox drug:Roflumilast drug:Homoharringtonine drug:ado-trastuzumab emtansine drug:Canakinumab drug:Sitaxentan drug:Tocilizumab drug:Denosumab drug:golimumab drug:Ivacaftor drug:Certolizumab pegol drug:DBSALT000180

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 56 triples

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