Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB08160"

Predicate	Value (sorted: none)
drugbank:description	" experimental This compound belongs to the thiazoles. These are heterocyclic compounds containing a five-member aromatic ring made up of one sulfur atom, one nitrogen, and three carbon atoms. Thiazoles Organic Compounds Heterocyclic Compounds Azoles Thiazoles Thioethers Carbonyl Hydrates Polyamines Monoalkylamines carbonyl hydrate polyamine thioether amine primary amine primary aliphatic amine organonitrogen compound logP -0.17 ALOGPS logS -1.8 ALOGPS Water Solubility 4.12e+00 g/l ALOGPS logP -0.081 ChemAxon IUPAC Name (2S)-2-amino-4-(methylsulfanyl)-1-(1,3-thiazol-2-yl)butane-1,1-diol ChemAxon Traditional IUPAC Name (2S)-2-amino-4-(methylsulfanyl)-1-(1,3-thiazol-2-yl)butane-1,1-diol ChemAxon Molecular Weight 234.339 ChemAxon Monoisotopic Weight 234.049669082 ChemAxon SMILES [H][C@](N)(CCSC)C(O)(O)C1=NC=CS1 ChemAxon Molecular Formula C8H14N2O2S2 ChemAxon InChI InChI=1S/C8H14N2O2S2/c1-13-4-2-6(9)8(11,12)7-10-3-5-14-7/h3,5-6,11-12H,2,4,9H2,1H3/t6-/m0/s1 ChemAxon InChIKey InChIKey=NPPGNJAWTLSRQG-LURJTMIESA-N ChemAxon Polar Surface Area (PSA) 79.37 ChemAxon Refractivity 58.15 ChemAxon Polarizability 23.54 ChemAxon Rotatable Bond Count 5 ChemAxon H Bond Acceptor Count 4 ChemAxon H Bond Donor Count 3 ChemAxon pKa (strongest acidic) 8.06 ChemAxon pKa (strongest basic) 9.84 ChemAxon Physiological Charge 1 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five true ChemAxon Ghose Filter true ChemAxon PubChem Compound 5288721 PubChem Substance 99444631 ChemSpider 4450821 PDB M3C BE0004187 Methionine aminopeptidase Staphylococcus aureus (strain Mu50 / ATCC 700699) # Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235 unknown Methionine aminopeptidase Translation, ribosomal structure and biogenesis Removes the amino-terminal methionine from nascent proteins map Cytoplasmic None 4.94 27502.1 Staphylococcus aureus (strain Mu50 / ATCC 700699) GeneCards map GenBank Gene Database BA000017 GenBank Protein Database 14245768 UniProtKB P0A078 UniProt Accession MAP1_STAAM MAP Peptidase M >Methionine aminopeptidase MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDE NFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQ KVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAH VLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTK DGPILTTKIEEE >1362 bp ATGTCGGAAAAAGAAATTTGGGAAAAAGTGCTTGAAATTGCTCAAGAAAAATTATCAGCT GTAAGTTACTCAACTTTCCTAAAAGATACTGAGCTTTACACGATTAAAGATGGTGAAGCT ATCGTATTATCGAGTATTCCTTTTAATGCAAATTGGTTAAATCAACAATATGCTGAAATT ATCCAAGCAATCTTATTTGATGTTGTAGGCTATGAAGTTAAACCTCACTTTATTACTACT GAAGAATTAGCAAATTATAGTAATAATGAAACTGCTACTCCAAAAGAAACAACAAAACCT TCTACTGAAACAACTGAGGATAATCATGTGCTTGGTAGAGAGCAATTCAATGCCCATAAC ACATTTGACACTTTTGTAATCGGACCTGGTAACCGCTTTCCACATGCAGCAAGTTTAGCT GTAGCCGAAGCACCAGCCAAAGCGTACAATCCATTATTTATCTATGGAGGGGTTGGTTTA GGAAAAACCCATTTAATGCATGCCATTGGTCATCATGTTTTAGATAATAATCCAGATGCC AAAGTGATTTACACATCAAGTGAAAAATTCACAAATGAATTTATTAAATCAATTCGTGAT AACGAAGGTGAAGCTTTCAGAGAAAGATATCGTAATATCGACGTCTTATTAATCGATGAT ATTCAGTTCATACAAAATAAAGTACAAACACAAGAAGAATTTTTCTATACTTTTAATGAA TTGCATCAGAATAACAAGCAAATAGTTATTTCGAGTGATCGACCACCAAAGGAAATTGCA CAATTAGAAGACCGATTACGTTCACGCTTTGAATGGGGGCTAATTGTTGATATTACGCCA CCAGATTATGAAACTCGAATGGCAATTTTGCAGAAGAAAATTGAAGAAGAAAAATTAGAT ATTCCACCAGAAGCTTTAAATTATATAGCAAATCAAATTCAATCTAATATTCGTGAATTA GAAGGTGCATTAACACGTTTACTTGCATATTCACAATTATTAGGAAAACCAATTACAACT GAATTAACTGCTGAAGCTTTAAAAGATATCATTCAAGCACCAAAATCTAAAAAGATTACC ATCCAAGATATTCAAAAAATTGTAGGCCAGTACTATAATGTTAGGATTGAAGATTTCAGT GCAAAAAAACGTACAAAGTCAATTGCATATCCGCGTCAAATAGCTATGTACTTGTCTAGA GAGCTTACAGATTTCTCATTACCTAAAATTGGTGAAGAATTTGGTGGGCGTGATCATACG ACCGTCATTCATGCTCATGAAAAAATATCTAAAGATTTAAAAGAAGATCCTATTTTTAAA CAAGAAGTAGAGAATCTTGAAAAAGAAATAAGAAATGTATAA PF00557 Peptidase_M24 function methionyl aminopeptidase activity function hydrolase activity function peptidase activity function metallopeptidase activity function exopeptidase activity function metalloexopeptidase activity function catalytic activity function aminopeptidase activity process metabolism process macromolecule metabolism process protein metabolism process cellular protein metabolism process proteolysis process physiological process "
rdf:type	drugbank:drugs
rdfs:label	"(2S)-2-AMINO-4-(METHYLSULFANYL)-1-(1,3-THIAZOL-2-YL)BUTANE-1,1-DIOL"

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

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