Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB06062"

PredicateValue (sorted: default)
rdfs:label
"XOMA 052"
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drugbank:description
"XOMA 052 is a potent anti-inflammatory monoclonal antibody targeting IL-1b and is being developed as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. XOMA 052 is also an IgG2 isotype, which reduces the possibility of antibody dependent cellular cytotoxicity. Blocking IL-1β with XOMA 052 offers a novel approach to the treatment and control of Type 2 diabetes. "

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