Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB05237"
Predicate | Value (sorted: default) |
---|---|
rdfs:label |
"rhMBL"
|
rdf:type | |
drugbank:description |
"rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three identical peptide chains of 32 kDa each.
Although MBL can form several oligomeric forms, there are indications that dimers and trimers are not biologically active and at least a tetramer form is needed for activation of complement."
|
drugbank:drugCategory |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object