Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB05217"

PredicateValue (sorted: default)
rdfs:label
"GMX1777"
rdf:type
drugbank:description
"GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis."
drugbank:drugCategory

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

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