Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB04286"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"beta-D-Ribopyranose"
|
| rdf:type | |
| drugbank:description |
"
experimental
This compound belongs to the hexoses. These are monosaccharides in which the sugar unit is a hexose.
Hexoses
Organic Compounds
Organooxygen Compounds
Carbohydrates and Carbohydrate Conjugates
Monosaccharides
Oxanes
Secondary Alcohols
1,2-Diols
Hemiacetals
Polyamines
oxane
hemiacetal
polyol
1,2-diol
secondary alcohol
polyamine
ether
alcohol
logP
-2.6
ALOGPS
logS
0.91
ALOGPS
Water Solubility
1.22e+03 g/l
ALOGPS
logP
-2.3
ChemAxon
IUPAC Name
(2R,3R,4R,5R)-oxane-2,3,4,5-tetrol
ChemAxon
Traditional IUPAC Name
β-D-ribopyranose
ChemAxon
Molecular Weight
150.1299
ChemAxon
Monoisotopic Weight
150.05282343
ChemAxon
SMILES
O[C@@H]1CO[C@@H](O)[C@H](O)[C@@H]1O
ChemAxon
Molecular Formula
C5H10O5
ChemAxon
InChI
InChI=1S/C5H10O5/c6-2-1-10-5(9)4(8)3(2)7/h2-9H,1H2/t2-,3-,4-,5-/m1/s1
ChemAxon
InChIKey
InChIKey=SRBFZHDQGSBBOR-TXICZTDVSA-N
ChemAxon
Polar Surface Area (PSA)
90.15
ChemAxon
Refractivity
29.96
ChemAxon
Polarizability
13.23
ChemAxon
Rotatable Bond Count
0
ChemAxon
H Bond Acceptor Count
5
ChemAxon
H Bond Donor Count
4
ChemAxon
pKa (strongest acidic)
11.31
ChemAxon
pKa (strongest basic)
-3.5
ChemAxon
Physiological Charge
0
ChemAxon
Number of Rings
1
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
ChEBI
27476
PDB
RIP
BE0001940
D-ribose-binding periplasmic protein
Escherichia coli (strain K12)
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
D-ribose-binding periplasmic protein
Carbohydrate transport and metabolism
Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis
rbsB
Periplasm
None
7.76
30951.0
Escherichia coli (strain K12)
GenBank Gene Database
K00511
GenBank Protein Database
147519
UniProtKB
P02925
UniProt Accession
RBSB_ECOLI
D-ribose-binding periplasmic protein precursor
>D-ribose-binding periplasmic protein precursor
MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLV
VLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATKG
EVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGTSAARERGEGFQQAVAAHKFN
VLASQPADFDRIKGLNVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKSDVMVVGFD
GTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKVLKGEKVQAKYPVDLKLVVKQ
>891 bp
ATGAACATGAAAAAACTGGCTACCCTGGTTTCCGCTGTTGCGCTAAGCGCCACCGTCAGT
GCGAATGCGATGGCAAAAGACACCATCGCGCTGGTGGTCTCCACGCTTAACAACCCGTTT
TTTGTATCGCTGAAAGATGGCGCGCAGAAAGAGGCGGATAAACTTGGCTATAACTTGGTG
GTGCTGGACTCCCAGAACAACCCGGCGAAAGAGCTGGCGAACGTGCAGGACTTAACCGTT
CGCGGCACAAAAATCCTGCTGATTAACCCGACCGACTCCGACGCAGTGGGTAATGCTGTG
AAGATGGCTAACCAAGCGAACATCCCGGTTATCACTCTTGACCGCCAAGCAACGAAAGGT
GAAGTGGTGAGCCACATTGCTTCTGATAACGTACTGGGCGGCAAAATCGCTGGTGATTAC
ATCGCGAAGAAAGCGGGTGAAGGTGCAAAAGTTATCGAGCTGCAAGGCATTGCTGGTACA
TCCGCAGCCCGTGAACGTGGCGAAGGCTTCCAGCAGGCCGTTGCTGCTCACAAGTTTAAT
GTTCTTGCCAGCCAGCCAGCAGATTTTGATCGCATTAAAGGTTTGAACGTAATGCAGAAC
CTGTTGACCGCTCATCCGGATGTTCAGGCTGTATTCGCGCAGAATGATGAAATGGCGCTG
GGGGCGCTGCGCGCACTGCAAACTGCCGGTAAATCGGATGTGATGGTCGTCGGATTTGAC
GGTACACCGGATGGCGAAAAAGCGGTGAATGATGGCAAACTGGCAGCGACTATCGCTCAG
CTACCCGATCAGATTGGCGCGAAAGGCGTCGAAACCGCAGATAAAGTGCTGAAAGGCGAG
AAAGTTCAGGCTAAGTATCCGGTTGATCTGAAACTGGTTGTTAAGCAGTAG
PF00532
Peripla_BP_1
BE0001942
D-ribose pyranase
Bacillus subtilis (strain 168)
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
D-ribose pyranase
Carbohydrate transport and metabolism
Involved in the high-affinity ribose membrane transport system
rbsD
Cell membrane; peripheral membrane protein (Potential)
None
4.95
14228.0
Bacillus subtilis (strain 168)
GenBank Gene Database
Z25798
GenBank Protein Database
397496
UniProtKB
P36946
UniProt Accession
RBSD_BACSU
>High affinity ribose transport protein rbsD
MKKHGILNSHLAKILADLGHTDKIVIADAGLPVPDGVLKIDLSLKPGLPAFQDTAAVLAE
EMAVEKVIAAAEIKASNQENAKFLENLFSEQEIEYLSHEEFKLLTKDAKAVIRTGEFTPY
ANCILQAGVLF
>396 bp
ATGAAAAAACACGGTATACTGAACAGCCATCTTGCCAAGATTTTAGCCGACCTTGGCCAC
ACTGATAAAATTGTCATCGCGGATGCCGGACTGCCGGTTCCTGACGGCGTTTTGAAAATT
GATCTTTCACTGAAGCCGGGCCTTCCGGCTTTCCAAGATACAGCGGCAGTACTGGCTGAG
GAAATGGCGGTCGAAAAAGTCATTGCTGCAGCTGAAATAAAAGCATCCAATCAGGAGAAT
GCGAAATTTCTAGAAAATCTTTTCTCTGAACAAGAGATTGAATACCTTTCTCACGAGGAG
TTTAAGCTGCTGACAAAAGATGCAAAGGCAGTCATAAGAACAGGAGAATTCACACCATAT
GCCAACTGCATCCTGCAGGCAGGTGTACTTTTCTAG
PF05025
RbsD_FucU
process
transport
process
carbohydrate transport
process
physiological process
process
cellular physiological process
"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object