Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB04206"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"Nz2-Tryptophan"
|
| rdf:type | |
| drugbank:description |
"
experimental
logP
-2.1
ALOGPS
logS
-1.6
ALOGPS
Water Solubility
5.20e+00 g/l
ALOGPS
logP
-2.2
ChemAxon
IUPAC Name
(2S)-2-amino-3-{pyrrolo[2,3-b]pyridin-3-yl}propanoic acid
ChemAxon
Traditional IUPAC Name
nz2-tryptophan
ChemAxon
Molecular Weight
204.2053
ChemAxon
Monoisotopic Weight
204.077301579
ChemAxon
SMILES
N[C@@H](Cc1cnc2ncccc12)C(O)=O
ChemAxon
Molecular Formula
C10H10N3O2
ChemAxon
Polar Surface Area (PSA)
89.1
ChemAxon
Refractivity
54.11
ChemAxon
Polarizability
20.09
ChemAxon
Rotatable Bond Count
3
ChemAxon
H Bond Acceptor Count
5
ChemAxon
H Bond Donor Count
2
ChemAxon
pKa (strongest acidic)
2.07
ChemAxon
pKa (strongest basic)
9.29
ChemAxon
Physiological Charge
0
ChemAxon
Number of Rings
2
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
PubChem Compound
7000165
PubChem Substance
46508068
PDB
TRN
BE0001993
Lysozyme
Enterobacteria phage lambda
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
Lysozyme
Involved in lysozyme activity
Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity. Acts as a transglycosylase. Cleaves glycosidic bonds between the C1 of N-acetyl muramic acids (NAM) and C4 of N-acetyl glucosamines (NAG) of the peptidoglycan of the bacterial walls
R
Cytoplasmic
None
9.66
17825.0
Enterobacteria phage lambda
GenBank Gene Database
J02459
GenBank Protein Database
215163
UniProtKB
P03706
UniProt Accession
LYS_LAMBD
EC 3.2.1.17
Endolysin
Lysis protein
Muramidase
>Lysozyme
MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLK
STGAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRC
SNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIDV
>477 bp
ATGGTAGAAATCAATAATCAACGTAAGGCGTTCCTCGATATGCTGGCGTGGTCGGAGGGA
ACTGATAACGGACGTCAGAAAACCAGAAATCATGGTTATGACGTCATTGTAGGCGGAGAG
CTATTTACTGATTACTCCGATCACCCTCGCAAACTTGTCACGCTAAACCCAAAACTCAAA
TCAACAGGCGCCGGACGCTACCAGCTTCTTTCCCGTTGGTGGGATGCCTACCGCAAGCAG
CTTGGCCTGAAAGACTTCTCTCCGAAAAGTCAGGACGCTGTGGCATTGCAGCAGATTAAG
GAGCGTGGCGCTTTACCTATGATTGATCGTGGTGATATCCGTCAGGCAATCGACCGTTGC
AGCAATATCTGGGCTTCACTGCCGGGCGCTGGTTATGGTCAGTTCGAGCATAAGGCTGAC
AGCCTGATTGCAAAATTCAAAGAAGCGGGCGGAACGGTCAGAGAGATTGATGTATGA
PF00959
Phage_lysozyme
function
hydrolase activity
function
hydrolase activity, acting on glycosyl bonds
function
hydrolase activity, hydrolyzing O-glycosyl compounds
function
lysozyme activity
function
catalytic activity
process
cellular catabolism
process
metabolism
process
cell wall catabolism
process
peptidoglycan catabolism
process
macromolecule metabolism
process
carbohydrate metabolism
process
cellular carbohydrate metabolism
process
peptidoglycan metabolism
process
physiological process
process
catabolism
"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object