Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB03138"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"Perchlorate Ion"
|
| rdf:type | |
| drugbank:description |
"
experimental
This compound belongs to the non-metal perchlorates. These are inorganic non-metallic compoundscontaining a perchlorate as its largest oxoanion.
Non-metal Perchlorates
Inorganic Compounds
Homogeneous Non-metal Compounds
Non-metal Oxoanionic Compounds
Non-metal Perchlorates
logP
-0.098
ChemAxon
IUPAC Name
perchlorate
ChemAxon
Traditional IUPAC Name
perchlorate ion
ChemAxon
Molecular Weight
99.451
ChemAxon
Monoisotopic Weight
98.948511195
ChemAxon
SMILES
[O-][Cl](=O)(=O)=O
ChemAxon
Molecular Formula
ClO4
ChemAxon
InChI
InChI=1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)/p-1
ChemAxon
InChIKey
InChIKey=VLTRZXGMWDSKGL-UHFFFAOYSA-M
ChemAxon
Polar Surface Area (PSA)
74.27
ChemAxon
Refractivity
11.91
ChemAxon
Polarizability
5.23
ChemAxon
Rotatable Bond Count
0
ChemAxon
H Bond Acceptor Count
4
ChemAxon
H Bond Donor Count
0
ChemAxon
pKa (strongest acidic)
-6.9
ChemAxon
Physiological Charge
-1
ChemAxon
Number of Rings
0
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
ChEBI
49706
PubChem Compound
123351
PubChem Substance
46506970
ChemSpider
109953
PDB
LCP
BE0001876
Protein ArsC
Staphylococcus aureus
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
Protein ArsC
Signal transduction mechanisms
Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances
arsC
Cytoplasmic
None
4.68
14813.0
Staphylococcus aureus
GenBank Gene Database
M86824
GenBank Protein Database
150729
UniProtKB
P0A006
UniProt Accession
ARSC_STAAU
Arsenate reductase
Arsenical pump modifier
EC 1.20.4.-
EC 3.1.3.48
Low molecular weight protein-tyrosine-phosphatase
>Protein arsC
MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDIS
NHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFDDPAGKEWSEFQRVRDE
IKLAIEKFKLR
>396 bp
ATGGATAAGAAAACAATTTATTTTATATGTACAGGAAACTCTTGTCGTAGCCAAATGGCT
GAAGGTTGGGGAAAGGAAATATTGGGTGAAGGTTGGAATGTCTATTCTGCTGGTATTGAA
ACACATGGTGTTAATCCTAAAGCAATAGAAGCTATGAAAGAAGTAGATATTGATATATCA
AACCATACGTCAGACTTGATTGATAATGATATTTTAAAACAATCAGATTTGGTCGTAACG
TTATGTAGTGATGCAGACAATAATTGTCCTATTTTACCACCAAACGTTAAAAAAGAGCAT
TGGGGTTTTGATGATCCAGCAGGTAAAGAATGGTCAGAATTCCAACGTGTTAGAGACGAG
ATTAAATTAGCTATAGAAAAGTTTAAATTGAGATAA
PF01451
LMWPc
function
hydrolase activity
function
hydrolase activity, acting on ester bonds
function
phosphoric ester hydrolase activity
function
phosphoric monoester hydrolase activity
function
phosphoprotein phosphatase activity
function
catalytic activity
function
protein tyrosine phosphatase activity
process
metabolism
process
protein amino acid dephosphorylation
process
macromolecule metabolism
process
biopolymer metabolism
process
biopolymer modification
process
protein modification
process
physiological process
"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object