Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB03095"
| Predicate | Value (sorted: none) |
|---|---|
| drugbank:description |
"
experimental
This compound belongs to the polyamines. These are compounds containing more than one amine group.
Polyamines
Organic Compounds
Organonitrogen Compounds
Amines
Polyamines
logP
-4.1
ALOGPS
logS
-2.9
ALOGPS
Water Solubility
1.33e-01 g/l
ALOGPS
logP
-4
ChemAxon
IUPAC Name
tetramethylazanium
ChemAxon
Traditional IUPAC Name
tetramethylammonium ion
ChemAxon
Molecular Weight
74.1448
ChemAxon
Monoisotopic Weight
74.096974389
ChemAxon
SMILES
C[N+](C)(C)C
ChemAxon
Molecular Formula
C4H12N
ChemAxon
InChI
InChI=1S/C4H12N/c1-5(2,3)4/h1-4H3/q+1
ChemAxon
InChIKey
InChIKey=QEMXHQIAXOOASZ-UHFFFAOYSA-N
ChemAxon
Polar Surface Area (PSA)
0
ChemAxon
Refractivity
35.9
ChemAxon
Polarizability
9.75
ChemAxon
Rotatable Bond Count
0
ChemAxon
H Bond Acceptor Count
0
ChemAxon
H Bond Donor Count
0
ChemAxon
Physiological Charge
1
ChemAxon
Number of Rings
0
ChemAxon
Bioavailability
1
ChemAxon
Rule of Five
true
ChemAxon
ChEBI
46020
PubChem Compound
6380
PubChem Substance
46507268
PDB
TMA
BE0001521
UDP-glucose 4-epimerase
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
UDP-glucose 4-epimerase
Cell wall/membrane/envelope biogenesis
Catalyzes two distinct but analogous reactions:the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine
GALE
1p36-p35
None
6.71
38282.0
Human
HUGO Gene Nomenclature Committee (HGNC)
HGNC:4116
GenAtlas
GALE
GeneCards
GALE
GenBank Gene Database
L41668
GenBank Protein Database
1119217
UniProtKB
Q14376
UniProt Accession
GALE_HUMAN
EC 5.1.3.2
Galactowaldenase
UDP-galactose 4-epimerase
>UDP-glucose 4-epimerase
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
>1047 bp
ATGGCAGAGAAGGTGCTGGTAACAGGTGGGGCTGGCTACATTGGCAGCCACACGGTGCTG
GAGCTGCTGGAGGCTGGCTACTTGCCTGTGGTCATCGATAACTTCCATAATGCCTTCCGT
GGAGGGGGCTCCCTGCCTGAGAGCCTGCGGCGGGTCCAGGAGCTGACAGGCCGCTCTGTG
GAGTTTGAGGAGATGGACATTTTGGACCAGGGAGCCCTACAGCGTCTCTTCAAAAAGTAC
AGCTTTATGGCGGTCATCCACTTTGCGGGGCTCAAGGCCGTGGGCGAGTCGGTGCAGAAG
CCTCTGGATTATTACAGAGTTAACCTGACCGGGACCATCCAGCTTCTGGAGATCATGAAG
GCCCACGGGGTGAAGAACCTGGTGTTCAGCAGCTCAGCCACTGTGTACGGGAACCCCCAG
TACCTGCCCCTTGATGAGGCCCACCCCACGGGTGGTTGTACCAACCCTTACGGCAAGTCC
AAGTTCTTCATCGAGGAAATGATCCGGGACCTGTGCCAGGCAGACAAGACTTGGAACGTA
GTGCTGCTGCGCTATTTCAACCCCACAGGTGCCCATGCCTCTGGCTGCATTGGTGAGGAT
CCCCAGGGCATACCCAACAACCTCATGCCTTATGTCTCCCAGGTGGCGATCGGGCGACGG
GAGGCCCTGAATGTCTTTGGCAATGACTATGACACAGAGGATGGCACAGGTGTCCGGGAT
TACATCCATGTCGTGGATCTGGCCAAGGGCCACATTGCAGCCTTAAGGAAGCTGAAAGAA
CAGTGTGGCTGCCGGATCTACAACCTGGGCACGGGCACAGGCTATTCAGTGCTGCAGATG
GTCCAGGCTATGGAGAAGGCCTCTGGGAAGAAGATCCCGTACAAGGTGGTGGCACGGCGG
GAAGGTGATGTGGCAGCCTGTTACGCCAACCCCAGCCTGGCCCAAGAGGAGCTGGGGTGG
ACAGCAGCCTTAGGGCTGGACAGGATGTGTGAGGATCTCTGGCGCTGGCAGAAGCAGAAT
CCTTCAGGCTTTGGCACGCAAGCCTGA
PF01370
Epimerase
function
catalytic activity
function
NAD binding
function
racemase and epimerase activity
function
cofactor binding
function
racemase and epimerase activity, acting on carbohydrates and derivatives
function
coenzyme binding
function
UDP-glucose 4-epimerase activity
function
isomerase activity
function
binding
process
monosaccharide metabolism
process
hexose metabolism
process
metabolism
process
cellular metabolism
process
nucleotide-sugar metabolism
process
macromolecule metabolism
process
galactose metabolism
process
carbohydrate metabolism
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
process
alcohol metabolism
process
physiological process
"
|
| rdf:type | |
| rdfs:label |
"Tetramethylammonium Ion"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object