Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB02681"
| Predicate | Value (sorted: default) |
|---|---|
| rdfs:label |
"Meta Vanadate"
|
| rdf:type | |
| drugbank:description |
"
experimental
This compound belongs to the miscellaneous vanadates. These are inorganic compounds in which the largest metallic oxoanion is vanadate, to which either no atom or a non metal atom is bonded.
Miscellaneous Vanadates
Inorganic Compounds
Mixed Metal/Non-metal Compounds
Miscellaneous Mixed Metal/Non-metals
Miscellaneous Metallic Oxoanionic Compounds
logP
-5.5
ChemAxon
IUPAC Name
2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium
ChemAxon
Traditional IUPAC Name
2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium
ChemAxon
Molecular Weight
660.5791
ChemAxon
Monoisotopic Weight
660.511123543
ChemAxon
SMILES
[O-][V](=O)[O+]([V](=O)O[V](=O)(=O)O[V](=O)(=O)[O+]([V]([O-])=O)[V](=O)(=O)=O)[V](=O)(=O)=O
ChemAxon
Molecular Formula
O19V7
ChemAxon
InChI
InChI=1S/19O.7V/q;;;;;;;;;;;;;;;2*-1;2*+1;;;;;;;
ChemAxon
InChIKey
InChIKey=ONZDNYIINYVFKD-UHFFFAOYSA-N
ChemAxon
Polar Surface Area (PSA)
313.67
ChemAxon
Refractivity
50.57
ChemAxon
Polarizability
33.91
ChemAxon
Rotatable Bond Count
10
ChemAxon
H Bond Acceptor Count
15
ChemAxon
H Bond Donor Count
0
ChemAxon
pKa (strongest acidic)
10.44
ChemAxon
pKa (strongest basic)
-7.2
ChemAxon
Physiological Charge
2
ChemAxon
Number of Rings
0
ChemAxon
Bioavailability
0
ChemAxon
PubChem Substance
46508307
PDB
V7O
BE0004552
Cyclin-dependent kinases regulatory subunit 1
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Cyclin-dependent kinases regulatory subunit 1
CKS1B
Human
UniProtKB
P61024
UniProt Accession
CKS1_HUMAN
BE0001224
Uridine phosphorylase
Escherichia coli (strain K12)
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
unknown
Uridine phosphorylase
Nucleotide transport and metabolism
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
udp
Cytoplasm
None
6.16
27159.0
Escherichia coli (strain K12)
GenBank Gene Database
X15689
GenBank Protein Database
43242
UniProtKB
P12758
UniProt Accession
UDP_ECOLI
EC 2.4.2.3
UPase
UrdPase
>Uridine phosphorylase
MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGK
PVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGAS
LHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFYPGQERYDTYSGRVVRHF
KGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESH
AVKIVVEAARRLL
>762 bp
ATGTCCAAGTCTGATGTTTTTCATCTCGGCCTCACTAAAAACGATTTACAAGGGGCTACG
CTTGCCATCGTCCCTGGCGACCCGGATCGTGTGGAAAAGATCGCCGCGCTGATGGATAAG
CCGGTTAAGCTGGCATCTCACCGCGAATTCACTACCTGGCGTGCAGAGCTGGATGGTAAA
CCTGTTATCGTCTGCTCTACCGGTATCGGCGGCCCGTCTACCTCTATTGCTGTTGAAGAG
CTGGCACAGCTGGGCATTCGCACCTTCCTGCGTATCGGTACAACGGGCGCTATTCAGCCG
CATATTAATGTGGGTGATGTCCTGGTTACCACGGCGTCTGTCCGTCTGGATGGCGCGAGC
CTGCACTTCGCACCGCTGGAATTCCCGGCTGTCGCTGATTTCGAATGTACGACTGCGCTG
GTTGAAGCTGCGAAATCCATTGGCGCGACAACTCACGTTGGCGTGACAGCTTCTTCTGAT
ACCTTCTACCCAGGTCAGGAACGTTACGATACTTACTCTGGTCGCGTAGTTCGTCACTTT
AAAGGTTCTATGGAAGAGTGGCAGGCGATGGGCGTAATGAACTATGAAATGGAATCTGCA
ACCCTGCTGACCATGTGTGCAAGTCAGGGCCTGCGTGCCGGTATGGTAGCGGGTGTTATC
GTTAACCGCACCCAGCAAGAGATCCCGAATGCTGAGACGATGAAACAAACCGAAAGCCAT
GCGGTGAAAATCGTGGTGGAAGCGGCGCGTCGTCTGCTGTAA
PF01048
PNP_UDP_1
component
cell
component
intracellular
component
cytoplasm
function
uridine phosphorylase activity
function
transferase activity
function
transferase activity, transferring glycosyl groups
function
transferase activity, transferring pentosyl groups
function
catalytic activity
process
nucleoside metabolism
process
metabolism
process
nucleotide catabolism
process
cellular metabolism
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
process
nucleotide metabolism
process
physiological process
"
|
| owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object