Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB02548"
| Predicate | Value (sorted: none) |
|---|---|
| rdfs:label |
"Sorbitol 6-phosphate"
|
| owl:sameAs | |
| drugbank:description |
"
20479-58-7
experimental
This compound belongs to the monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked tot he carbohydrate unit.
Monosaccharide Phosphates
Organic Compounds
Organooxygen Compounds
Carbohydrates and Carbohydrate Conjugates
Monosaccharides
Hexoses
Organophosphate Esters
Organic Phosphoric Acids
Secondary Alcohols
1,2-Diols
Primary Alcohols
Polyamines
organic phosphate
phosphoric acid ester
secondary alcohol
polyol
1,2-diol
primary alcohol
polyamine
alcohol
1-O-phosphono-D-glucitol
D-glucitol-6-phosphate
logP
-2.3
ALOGPS
logS
-0.99
ALOGPS
Water Solubility
2.66e+01 g/l
ALOGPS
logP
-3.9
ChemAxon
IUPAC Name
{[(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexyl]oxy}phosphonic acid
ChemAxon
Traditional IUPAC Name
[(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexyl]oxyphosphonic acid
ChemAxon
Molecular Weight
262.1517
ChemAxon
Monoisotopic Weight
262.04536859
ChemAxon
SMILES
OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O
ChemAxon
Molecular Formula
C6H15O9P
ChemAxon
InChI
InChI=1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)/t3-,4-,5+,6+/m1/s1
ChemAxon
InChIKey
InChIKey=GACTWZZMVMUKNG-ZXXMMSQZSA-N
ChemAxon
Polar Surface Area (PSA)
167.91
ChemAxon
Refractivity
49.28
ChemAxon
Polarizability
21.66
ChemAxon
Rotatable Bond Count
7
ChemAxon
H Bond Acceptor Count
8
ChemAxon
H Bond Donor Count
7
ChemAxon
pKa (strongest acidic)
1.49
ChemAxon
pKa (strongest basic)
-3
ChemAxon
Physiological Charge
-2
ChemAxon
Number of Rings
0
ChemAxon
Bioavailability
1
ChemAxon
ChEBI
17044
PubChem Compound
14620017
PubChem Substance
46508367
KEGG Compound
C01096
ChemSpider
598
PDB
S6P
BE0001199
Glucose-6-phosphate isomerase
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Glucose-6-phosphate isomerase
Carbohydrate transport and metabolism
Neuroleukin is a neurotrophic factor for spinal and sensory neurons
GPI
19q13.1
Cytoplasm
None
8.55
63148.0
Human
HUGO Gene Nomenclature Committee (HGNC)
HGNC:4458
GenAtlas
GPI
GeneCards
GPI
GenBank Gene Database
K03515
GenBank Protein Database
189238
UniProtKB
P06744
UniProt Accession
G6PI_HUMAN
EC 5.3.1.9
GPI
Neuroleukin
NLK
PGI
PHI
Phosphoglucose isomerase
Phosphohexose isomerase
SA-36
Sperm antigen 36
>Glucose-6-phosphate isomerase
MAALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLNTNHGHILVDYSKNLV
TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP
EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR
VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVA
KHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGA
HWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESN
GKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGL
HHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFT
KLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDA
STNGLINFIKQQREARVQ
>1677 bp
ATGGCCGCTCTCACCCGGGACCCCCAGTTCCAGAAGCTGCAGCAATGGTACCGCGAGCAC
CGCTCCGAGCTGAACCTGCGCCGCCTCTTCGATGCCAACAAGGACCGCTTCAACCACTTC
AGCTTGACCCTCAACACCAACCATGGGCATATCCTGGTGGATTACTCCAAGAACCTGGTG
ACGGAGGACGTGATGCGGATGCTGGTGGACTTGGCCAAGTCCAGGGGCGTGGAGGCCGCC
CGGGAGCGGATGTTCAATGGTGAGAAGATCAACTACACCGAGGGTCGAGCCGTGCTGCAC
GTGGCTCTGCGGAACCGGTCAAACACACCCATCCTGGTAGACGGCAAGGATGTGATGCCA
GAGGTCAACAAGGTTCTGGACAAGATGAAGTCTTTCTGCCAGCGTGTCCGGAGCGGTGAC
TGGAAGGGGTACACAGGCAAGACCATCACGGACGTCATCAACATTGGCATTGTCGGCTCC
GACCTGGGACCCCTCATGGTGACTGAAGCCCTTAAGCCATACTCTTCAGGAGGTCCCCGC
GTCTGGTATGTCTCCAACATTGATGGAACTCACATTGCCAAAACCCTGGCCCAGCTGAAC
CCGGAGTCCTCCCTGTTCATCATTGCCTCCAAGACCTTTACTACCCAGGAGACCATCACG
AATGCAGAGACGGCGAAGGAGTGGTTTCTCCAGGCGGCCAAGGATCCTTCTGCAGTGGCG
AAGCACTTTGTTGCCCTGTCTACTAACACAACCAAAGTGAAGGAGTTTGGAATTGACCCT
CAAAACATGTTCGAGTTCTGGGATTGGGTGGGAGGACGCTACTCGCTGTGGTCGGCCATC
GGACTCTCCATTGCCCTGCACGTGGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCT
CACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTG
GCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCC
TATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAAT
GGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGG
GGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAG
ATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTG
CATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAA
TCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAG
AGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCTATTGTGTTCACC
AAGCTCACACCATTCATGCTTGGAGCCTTGGTCGCCATGTATGAGCACAAGATCTTCGTT
CAGGGCATCATCTGGGACATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAG
CTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGACGCT
TCTACCAATGGGCTCATCAACTTCATCAAGCAGCAGCGCGAGGCCAGAGTCCAATAA
PF00342
PGI
function
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
function
glucose-6-phosphate isomerase activity
function
isomerase activity
function
intramolecular oxidoreductase activity
function
catalytic activity
process
metabolism
process
gluconeogenesis
process
cellular metabolism
process
alcohol metabolism
process
monosaccharide metabolism
process
hexose metabolism
process
glucose metabolism
process
glucose catabolism
process
physiological process
process
glycolysis
"
|
| rdf:type |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource does not appear as an object