Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB02317"

Predicate	Value (sorted: default)
rdfs:label	"Alpha-D-Galactose-1-Phosphate"
rdf:type	drugbank:drugs
drugbank:description	" 2255-14-3 experimental This compound belongs to the hexose phosphates. These are carbohydrate derivatives containing an hexose substituted by one or more phosphate groups. Hexose Phosphates Organic Compounds Organooxygen Compounds Carbohydrates and Carbohydrate Conjugates Monosaccharides Monosaccharide Phosphates Organophosphate Esters Organic Phosphoric Acids Oxanes Secondary Alcohols 1,2-Diols Primary Alcohols Ethers Polyamines monosaccharide phosphate oxane phosphoric acid ester organic phosphate secondary alcohol polyol 1,2-diol polyamine primary alcohol ether alcohol logP -2 ALOGPS logS -0.91 ALOGPS Water Solubility 3.23e+01 g/l ALOGPS logP -3.1 ChemAxon IUPAC Name {[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid ChemAxon Traditional IUPAC Name [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphonic acid ChemAxon Molecular Weight 260.1358 ChemAxon Monoisotopic Weight 260.029718526 ChemAxon SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O ChemAxon Molecular Formula C6H13O9P ChemAxon InChI InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3+,4+,5-,6-/m1/s1 ChemAxon InChIKey InChIKey=HXXFSFRBOHSIMQ-FPRJBGLDSA-N ChemAxon Polar Surface Area (PSA) 156.91 ChemAxon Refractivity 46.8 ChemAxon Polarizability 20.62 ChemAxon Rotatable Bond Count 3 ChemAxon H Bond Acceptor Count 8 ChemAxon H Bond Donor Count 6 ChemAxon pKa (strongest acidic) 1.16 ChemAxon pKa (strongest basic) -3 ChemAxon Physiological Charge -2 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon ChEBI 17973 PubChem Compound 123912 PubChem Substance 46508735 KEGG Compound C00446 ChemSpider 453 PDB GL1 SMP00580 GLUT-1 deficiency syndrome DB01373 Calcium DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate DB03435 Uridine-5'-Diphosphate DB03685 Uridine-5'-Monophosphate DB04465 Lactose P35575 Q16851 P22392 P30085 P07902 P11166 P00709 P15291 Q8WVQ1 P78381 SMP00579 Congenital disorder of glycosylation CDG-IId DB01373 Calcium DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate DB03435 Uridine-5'-Diphosphate DB03685 Uridine-5'-Monophosphate DB04465 Lactose P35575 Q16851 P22392 P30085 P07902 P11166 P00709 P15291 Q8WVQ1 P78381 SMP00043 Galactose Metabolism DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate DB03435 Uridine-5'-Diphosphate DB04077 Glycerol DB04465 Lactose P06280 P10253 Q53H18 P15121 P51570 P15291 P07902 Q14376 Q16851 P36871 P35575 P19367 P35557 P09848 SMP00496 Galactosemia III DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate P35557 P36871 Q16851 O60701 Q8NBZ7 P07902 P51570 Q14376 SMP00495 Galactosemia II (GALK) DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate P35557 P36871 Q16851 O60701 Q8NBZ7 P07902 P51570 Q14376 SMP00182 Galactosemia DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate DB03435 Uridine-5'-Diphosphate DB04077 Glycerol DB04465 Lactose P06280 P10253 Q53H18 P15121 P51570 P15291 P07902 Q14376 Q16851 P36871 P35575 P19367 P35557 P09848 SMP00444 Lactose Synthesis DB01373 Calcium DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate DB03435 Uridine-5'-Diphosphate DB03685 Uridine-5'-Monophosphate DB04465 Lactose P35575 Q16851 P22392 P30085 P07902 P11166 P00709 P15291 Q8WVQ1 P78381 SMP00010 Nucleotide Sugars Metabolism DB01592 Iron DB01593 Zinc DB01861 Glucose-Uridine-C1,5'-Diphosphate DB02317 Alpha-D-Galactose-1-Phosphate P35557 P36871 Q16851 O60701 Q8NBZ7 P07902 P51570 Q14376 BE0001357 Beta-phosphoglucomutase Lactococcus lactis subsp. lactis (strain IL1403) # Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284 # Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423 unknown Beta-phosphoglucomutase Involved in phosphoglucomutase activity Reversible transformation of glucose 6-phosphate and beta-glucose 1-phosphate pgmB Cytoplasmic None 4.6 24209.0 Lactococcus lactis subsp. lactis (strain IL1403) GenBank Gene Database Z70730 GenBank Protein Database 1495997 UniProtKB P71447 UniProt Accession PGMB_LACLA Beta-PGM EC 5.4.2.6 >Beta-phosphoglucomutase MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSREDSLQKILDLA DKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLLKDLRSNKIKIALASASKNGP FLLEKMNLTGYFDAIADPAEVAASKPAPDIFIAAAHAVGVAPSESIGLEDSQAGIQAIKD SGALPIGVGRPEDLGDDIVIVPDTSYYTLEFLKEVWLQKQK >666 bp ATGTTTAAAGCAGTATTGTTTGATTTAGATGGTGTAATTACAGATACCGCAGAGTATCAT TTTAGAGCTTGGAAAGCTTTGGCTGAAGAAATTGGCATTAATGGTGTTGACCGCCAATTT AATGAGCAATTAAAAGGGGTCTCACGAGAAGACTCGCTTCAGAAAATTCTAGATTTAGCT GATAAAAAAGTATCAGCTGAGGAATTTAAAGAACTTGCTAAGAGAAAAAATGATAACTAT GTGAAAATGATTCAGGATGTGTCGCCAGCCGATGTCTATCCTGGAATTTTACAATTACTC AAAGATTTACGTTCAAATAAAATCAAAATTGCTTTAGCGTCGGCTTCTAAGAATGGTCCA TTTTTATTAGAGAGAATGAATTTAACTGGATATTTTGATGCAATTGCTGATCCGGCTGAA GTTGCAGCATCAAAACCAGCACCAGATATTTTTATTGCAGCAGCACATGCAGTGGGTGTT GCCCCCTCTGAATCAATTGGGTTAGAGGATTCTCAAGCTGGAATTCAAGCCATCAAAGAT TCAGGGGCTTTACCAATTGGTGTAGGGCGCCCAGAAGATTTGGGAGATGATATCGTCATT GTGCCTGATACTTCACACTATACATTAGAATTTTTGAAAGAAGTTTGGCTTCAAAAGCAA AAATAA PF00702 Hydrolase function hydrolase activity function catalytic activity process physiological process process metabolism "
owl:sameAs	drug:Calcium drug:Iron drug:Zinc drug:Glucose-Uridine-C1,5'-Diphosphate drug:Alpha-D-Galactose-1-Phosphate drug:Uridine-5'-Diphosphate drug:Uridine-5'-Monophosphate drug:Glycerol drug:Lactose drug:EXPT01595

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 9 triples

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