Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01700"
Predicate | Value (sorted: default) |
---|---|
rdfs:label |
"Aicar"
|
rdf:type | |
drugbank:description |
"
3031-94-5
experimental
This compound belongs to the 1-phosphoribosyl-imidazoles. These are organic compounds containing the imidazole ring linked to a ribose phosphate through a 1-2 bond.
1-Phosphoribosyl-imidazoles
Organic Compounds
Organooxygen Compounds
Carbohydrates and Carbohydrate Conjugates
Glycosyl Compounds
1-Ribosyl-imidazolecarboxamides
Pentose Phosphates
Monosaccharide Phosphates
Carbonylimidazoles
Organic Phosphoric Acids
Primary Aromatic Amines
Aminoimidazoles
Organophosphate Esters
N-substituted Imidazoles
Tetrahydrofurans
Oxolanes
Secondary Alcohols
Primary Carboxylic Acid Amides
1,2-Diols
Polyamines
Enolates
Ethers
Carboxylic Acids
pentose-5-phosphate
pentose phosphate
monosaccharide phosphate
pentose monosaccharide
imidazole-4-carbonyl group
aminoimidazole
primary aromatic amine
monosaccharide
phosphoric acid ester
organic phosphate
n-substituted imidazole
tetrahydrofuran
oxolane
azole
imidazole
carboxamide group
primary carboxylic acid amide
secondary alcohol
1,2-diol
enolate
carboxylic acid derivative
polyamine
carboxylic acid
ether
primary amine
organonitrogen compound
alcohol
amine
logP
-2.2
ALOGPS
logS
-2.1
ALOGPS
Water Solubility
2.79e+00 g/l
ALOGPS
logP
-4.8
ChemAxon
IUPAC Name
{[(2S,3R,4R,5R)-5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
ChemAxon
Traditional IUPAC Name
[(2S,3R,4R,5R)-5-(5-amino-4-carbamoylimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid
ChemAxon
Molecular Weight
338.2112
ChemAxon
Monoisotopic Weight
338.062749988
ChemAxon
SMILES
NC(=O)C1=C(N)N(C=N1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
ChemAxon
Molecular Formula
C9H15N4O8P
ChemAxon
InChI
InChI=1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)/t3-,5-,6+,9+/m0/s1
ChemAxon
InChIKey
InChIKey=NOTGFIUVDGNKRI-BZKDHIKHSA-N
ChemAxon
Polar Surface Area (PSA)
203.38
ChemAxon
Refractivity
69.14
ChemAxon
Polarizability
28.61
ChemAxon
Rotatable Bond Count
5
ChemAxon
H Bond Acceptor Count
9
ChemAxon
H Bond Donor Count
6
ChemAxon
pKa (strongest acidic)
1.22
ChemAxon
pKa (strongest basic)
4.8
ChemAxon
Physiological Charge
-2
ChemAxon
Number of Rings
2
ChemAxon
Bioavailability
0
ChemAxon
ChEBI
18406
PubChem Compound
46936194
PubChem Substance
46508570
KEGG Compound
C04677
ChemSpider
195
BindingDB
22579
PDB
AC4
SMP00427
Azathioprine Action Pathway
DB00116
Tetrahydrofolic acid
DB00118
S-Adenosylmethionine
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB00993
Azathioprine
DB01033
Mercaptopurine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P00492
P20839
P49915
P51580
P63000
Q06278
Q06203
Q14542
Q9HAS3
Q99808
O43868
O15440
O15439
P47989
P55263
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
Q9Y2T3
Q9UKK9
P21108
P22102
O15067
P22234
P30566
P31939
Q9BY32
P36959
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00430
Thioguanine Action Pathway
DB00116
Tetrahydrofolic acid
DB00118
S-Adenosylmethionine
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00352
Tioguanine
DB00640
Adenosine
DB01033
Mercaptopurine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P00492
P20839
P49915
P51580
P63000
Q06278
Q06203
Q14542
Q9HAS3
Q99808
O43868
O15440
O15439
P47989
P55263
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
Q9Y2T3
Q9UKK9
P21108
P22102
O15067
P22234
P30566
P31939
Q9BY32
P36959
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00428
Mercaptopurine Action Pathway
DB00116
Tetrahydrofolic acid
DB00118
S-Adenosylmethionine
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01033
Mercaptopurine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P00492
P20839
P49915
P51580
P63000
Q06278
Q06203
Q14542
Q9HAS3
Q99808
O43868
O15440
O15439
P47989
P55263
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
Q9Y2T3
Q9UKK9
P21108
P22102
O15067
P22234
P30566
P31939
Q9BY32
P36959
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00535
Adenine phosphoribosyltransferase deficiency (APRT)
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00144
Adenosine Deaminase Deficiency
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00167
Adenylosuccinate Lyase Deficiency
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00168
AICA-Ribosiduria
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00203
Molybdenium Cofactor Deficiency
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00537
Myoadenylate deaminase deficiency
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00220
Xanthine Dehydrogenase Deficiency (Xanthinuria)
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00210
Purine Nucleoside Phosphorylase Deficiency
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00536
Mitochondrial DNA depletion syndrome
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00365
Gout or Kelley-Seegmiller Syndrome
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00512
Xanthinuria type I
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00513
Xanthinuria type II
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00364
Lesch-Nyhan Syndrome (LNS)
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
SMP00050
Purine Metabolism
DB00116
Tetrahydrofolic acid
DB00128
L-Aspartic Acid
DB00130
L-Glutamine
DB00142
L-Glutamic Acid
DB00145
Glycine
DB00640
Adenosine
DB01345
Potassium
DB01373
Calcium
DB01593
Zinc
DB01677
Fumarate
DB01696
7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione
DB01700
Aicar
DB01972
Guanosine-5'-Monophosphate
DB02134
Xanthine
DB02377
Guanine
DB02527
Cyclic Adenosine Monophosphate
DB02857
Guanosine
DB04076
Hypoxanthine
DB04335
Inosine
P50583
O75414
O75356
Q5MY95
Q16774
P49902
Q16854
P07741
P00491
P00492
Q9Y2T3
Q9UKK9
P21108
Q06203
P22102
O15067
P22234
P30566
P31939
Q9BY32
P49915
P20839
P36959
P47989
P30520
P23109
P00813
P00568
Q8NBU5
Q08499
Q96PN6
P33402
Q02153
Q9Y233
P10599
P23921
P31350
BE0001240
Bifunctional purine biosynthesis protein PURH
Human
# Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17139284
# Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17016423
# Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/10592235
unknown
Bifunctional purine biosynthesis protein PURH
Nucleotide transport and metabolism
10-formyltetrahydrofolate + 5-amino-1-(5- phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5- formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
ATIC
2q35
Cytoplasmic
None
6.7
64616.0
Human
HUGO Gene Nomenclature Committee (HGNC)
HGNC:794
GenAtlas
ATIC
GeneCards
ATIC
GenBank Gene Database
U37436
GenBank Protein Database
1263196
UniProtKB
P31939
UniProt Accession
PUR9_HUMAN
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase
AICAR transformylase
EC 2.1.2.3
EC 3.5.4.10
IMP cyclohydrolase
IMP synthetase
Inosinicase
>Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase
MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
>1776 bp
ATGTCTTCTCTCTCAGCCTTATTTAGTGTCTCTGACAAAACCGGCCTTGTGGAATTTGCA
AGAAACCTGACCGCTCTTGGTTTGAACCTGGTCGCTTCCGGAGGGACTGCAAAAGCTCTC
AGGGATGCTGGTCTGGCAGTCAGAGATGTCTCTGAGTTGACGGGATTTCCTGAAATGTTG
GGGGGACGTGTGAAAACTTTGCATCCTGCAGTCCATGCTGGAATCCTAGCTCGTAATATT
CCAGAAGATAATGCTGACATGGCCAGACTTGATTTCAATCTTATAAGAGTTGTCGCCTGC
AATCTCTATCCCTTTGTAAAGACAGTGGCTTCTCCAGGTGTAACTGTTGAGGAGGCTGTG
GAGCAAATTGACATTGGTGGAGTAACCTTACTGAGAGCTGCAGCCAAAAACCACGCTCGA
GTGACAGTGGTGTGTGAACCAGAGGACTATGTGGTGGTGTCCACGGAGATGCAGAGCTCC
GAGAGTAAGGGCACCTCCTTGGAGACTAGACGCCAGTTAGCCTTGAAGGCATTCACTCAT
ACGGCACAATATGATGAAGCAATTTCAGATTATTTCAGGAAACAGTACAGCAAAGGCGTA
TCTCAGATGCCCTTGAGATATGGAATGAACCCACATCAGACCCCTGCCCAGCTGTACACA
CTGCAGCCCAAGCTTCCCATCACAGTTCTAAATGGAGCCCCTGGATTTATAAACTTGTGC
GATGCTTTGAACGCCTGGCAGCTGGTGAAGGAACTCAAGGAGGCTTTAGGTATTCCAGCC
GCTGCCTCTTTCAAACATGTCAGCCCAGCAGGTGCTGCTGTTGGAATTCCACTCAGTGAA
GATGAGGCCAAAGTCTGCATGGTTTATGATCTCTATAAAACCCTCACACCCATCTCAGCG
GCATATGCAAGAGCAAGAGGGGCTGATAGGATGTCTTCATTTGGTGATTTTGTTGCATTG
TCTGATGTTTGTGATGTACCAACTGCAAAAATTATTTCCAGAGAAGTATCTGATGGTATA
ATTGCCCCAGGATATGAAGAAGAAGCCTTGACAATACTTTCCAAAAAGAAAAATGGAAAC
TATTGTGTCCTTCAGATGGACCAATCTTACAAACCAGATGAAAATGAAGTTCGAACTCTC
TTTGGTCTTCATTTAAGCCAGAAGAGAAATAATGGTGTCGTCGACAAGTCATTATTTAGC
AATGTTGTTACCAAAAATAAAGATTTGCCAGAGTCTGCCCTCCGAGACCTCATCGTAGCC
ACCATTGCTGTCAAGTACACTCAGTCTAACTCTGTGTGCTACGCCAAGAACGGGCAGGTT
ATCGGCATTGGAGCAGGACAGCAGTCTCGTATACACTGCACTCGCCTTGCAGGAGATAAG
GCAAACTATTGGTGGCTTAGACACCATCCACAAGTGCTTTCGATGAAGTTTAAAACAGGA
GTGAAGAGAGCAGAAATCTCCAATGCCATCGATCAATATGTGACTGGAACCATTGGCGAG
GATGAAGATTTGATAAAGTGGAAGGCACTGTTTGAGGAAGTCCCTGAGTTACTCACTGAG
GCAGAGAAGAAGGAATGGGTTGAGAAACTGACTGAAGTTTCTATCAGCTCTGATGCCTTC
TTCCCTTTCCGAGATAACGTAGACAGAGCTAAAAGGAGTGGTGTGGCGTACATTGCGGCT
CCCTCCGGTTCTGCTGCTGACAAAGTTGTGATTGAGGCCTGCGACGAACTGGGAATCATC
CTCGCTCATACGAACCTTCGGCTCTTCCACCACTGA
PF01808
AICARFT_IMPCHas
PF02142
MGS
function
transferase activity
function
phosphoribosylaminoimidazolecarboxamide formyltransferase activity
function
transferase activity, transferring one-carbon groups
function
IMP cyclohydrolase activity
function
methyltransferase activity
function
glycine hydroxymethyltransferase activity
function
catalytic activity
function
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
function
hydrolase activity
function
hydroxymethyl-, formyl- and related transferase activity
function
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
function
cyclohydrolase activity
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
process
nucleotide metabolism
process
physiological process
process
purine nucleotide metabolism
process
metabolism
process
purine nucleotide biosynthesis
process
cellular metabolism
"
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owl:sameAs |
All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt
The resource appears as object in 23 triples