Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01115"

Predicate	Value (sorted: default)
rdfs:label	"Nifedipine"
rdf:type	drugbank:drugs
drugbank:description	"Nifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nifedipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Nifedipine is used to treat hypertension and chronic stable angina."
drugbank:drugCategory	drugcategory:Dihydropyridines
drugbank:interactsWith	drug:Cyclosporine drug:Butabarbital drug:Butalbital drug:Talbutal drug:Pentobarbital drug:Treprostinil drug:Tacrine drug:Secobarbital drug:Methohexital drug:Cimetidine drug:Voriconazole drug:Thiopental drug:Cisapride drug:Imatinib drug:Tizanidine drug:Primidone drug:Methylphenobarbital drug:Tacrolimus drug:Quinidine drug:Tipranavir drug:Telithromycin drug:Rifampicin drug:Melatonin drug:Phenobarbital drug:St. John's Wort drug:Dihydroquinidine barbiturate drug:Quinidine barbiturate drug:Amobarbital drug:Aprobarbital drug:Butethal drug:Heptabarbital drug:Hexobarbital drug:Quinupristin drug:Ginseng drug:Etravirine
owl:sameAs	drug:APRD00590 drug:BE0002638 drug:Cyclosporine drug:Butabarbital drug:Butalbital drug:Talbutal drug:Pentobarbital drug:Treprostinil drug:Tacrine drug:Secobarbital drug:Methohexital drug:Cimetidine drug:Voriconazole drug:Thiopental drug:Cisapride drug:Imatinib drug:Tizanidine drug:Primidone drug:Methylphenobarbital drug:Tacrolimus drug:Quinidine drug:Tipranavir drug:Telithromycin drug:Rifampicin drug:Melatonin drug:Nifedipine drug:Phenobarbital drug:St. John's Wort drug:Dihydroquinidine barbiturate drug:Potassium drug:Quinidine barbiturate drug:Amobarbital drug:Aprobarbital drug:Butethal drug:Heptabarbital drug:Hexobarbital drug:Quinupristin drug:Calcium drug:Ginseng drug:Etravirine drug:DBMET00380

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 73 triples

Context graph