Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01109"

PredicateValue (sorted: default)
rdfs:label
"Heparin"
rdf:type
drugbank:drugs
drugbank:description
"Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate."
drugbank:drugCategory
drugcategory:Anticoagulants
drugcategory:Fibrinolytic Agents
drugcategory:Heparins
drugbank:interactsWith
drug:Drotrecogin alfa
drug:Ticlopidine
drug:Treprostinil
drug:Tobramycin
drug:Acetylsalicylic acid
drug:Ginkgo biloba
drug:Drospirenone
drug:corticotropin-releasing factor
drug:Aprotinin
owl:sameAs
drug:APRD00056
drug:Drotrecogin alfa
drug:Ticlopidine
drug:Treprostinil
drug:Tobramycin
drug:Acetylsalicylic acid
drug:Heparin
drug:Calcium
drug:Ginkgo biloba
drug:Drospirenone
drug:Zinc
drug:Arachidonic Acid
drug:corticotropin-releasing factor
drug:Aprotinin
drug:DBSALT000417

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 22 triples

Context graph