Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB01104"

Predicate	Value (sorted: none)
owl:sameAs	drug:DBSALT000808
drugbank:drugCategory	drugcategory:Antidepressive Agents
owl:sameAs	drug:Oxycodone
drugbank:interactsWith	drug:Metoprolol
owl:sameAs	drug:Tipranavir
owl:sameAs	drug:Tranylcypromine
drugbank:interactsWith	drug:Tolterodine
owl:sameAs	drug:Trazodone
owl:sameAs	drug:Terbinafine
owl:sameAs	drug:Eletriptan
drugbank:interactsWith	drug:Trimipramine
drugbank:interactsWith	drug:Erythromycin
drugbank:interactsWith	drug:Phenytoin
drugbank:interactsWith	drug:Terbinafine
owl:sameAs	drug:Propafenone
owl:sameAs	drug:Erythromycin
owl:sameAs	drug:Sertraline
drugbank:interactsWith	drug:Eletriptan
drugbank:interactsWith	drug:Desvenlafaxine
drugbank:interactsWith	drug:Linezolid
drugbank:interactsWith	drug:Propranolol
owl:sameAs	drug:Linezolid
owl:sameAs	drug:Ginkgo biloba
owl:sameAs	drug:Frovatriptan
owl:sameAs	drug:Galantamine
drugbank:interactsWith	drug:Oxycodone
owl:sameAs	drug:Rasagiline
drugbank:drugCategory	drugcategory:Serotonin Uptake Inhibitors
owl:sameAs	drug:BE0002638
drugbank:interactsWith	drug:Ketoprofen
drugbank:interactsWith	drug:Treprostinil
owl:sameAs	drug:Naratriptan
owl:sameAs	drug:Fosphenytoin
owl:sameAs	drug:Carbamazepine
drugbank:interactsWith	drug:Tranylcypromine
owl:sameAs	drug:Tolmetin
owl:sameAs	drug:Zolmitriptan
owl:sameAs	drug:Metoprolol
owl:sameAs	drug:Phenytoin
rdf:type	drugbank:drugs
drugbank:interactsWith	drug:Triprolidine
owl:sameAs	drug:Tamoxifen
drugbank:interactsWith	drug:Tipranavir
owl:sameAs	drug:Tramadol
drugbank:interactsWith	drug:Pimozide
owl:sameAs	drug:Donepezil
owl:sameAs	drug:Isocarboxazid
owl:sameAs	drug:Cilostazol
drugbank:interactsWith	drug:Propafenone
drugbank:interactsWith	drug:Cilostazol
drugbank:interactsWith	drug:Donepezil
drugbank:interactsWith	drug:Clarithromycin
rdfs:label	"Sertraline"
drugbank:interactsWith	drug:Fosphenytoin
drugbank:interactsWith	drug:Almotriptan
drugbank:interactsWith	drug:Tramadol
owl:sameAs	drug:Tolterodine
drugbank:interactsWith	drug:Frovatriptan
drugbank:interactsWith	drug:Zolmitriptan
owl:sameAs	drug:Tamsulosin
drugbank:interactsWith	drug:Venlafaxine
owl:sameAs	drug:Triprolidine
drugbank:interactsWith	drug:Carbamazepine
owl:sameAs	drug:Treprostinil
drugbank:interactsWith	drug:Carvedilol
owl:sameAs	drug:Tiaprofenic acid
owl:sameAs	drug:Almotriptan
drugbank:interactsWith	drug:Naratriptan
owl:sameAs	drug:Propranolol
drugbank:interactsWith	drug:Tolmetin
drugbank:interactsWith	drug:Galantamine
drugbank:interactsWith	drug:Phenelzine
owl:sameAs	drug:APRD00175
drugbank:interactsWith	drug:Clozapine
drugbank:interactsWith	drug:Rasagiline
owl:sameAs	drug:Venlafaxine
owl:sameAs	drug:DBMET00335
drugbank:description	"Sertraline hydrochloride belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake. They have little to no effect on norepinephrine or dopamine reuptake and do not antagonize &alpha;- or &beta;-adrenergic, dopamine D<sub>2</sub> or histamine H<sub>1</sub> receptors. During acute use, SSRIs block serotonin reuptake and increase serotonin stimulation of somatodendritic 5-HT<sub>1A</sub> and terminal autoreceptors. Chronic use leads to desensitization of somatodendritic 5-HT<sub>1A</sub> and terminal autoreceptors. The overall clinical effect of increased mood and decreased anxiety is thought to be due to adaptive changes in neuronal function that leads to enhanced serotonergic neurotransmission. Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction and headache (see Toxicity section below for a more detailed listing of side effects). Compared to other agents in this class, sertraline may cause greater diarrheal and male sexual dysfunction effects. Side effects generally occur within the first two weeks of therapy and are usually less severe and frequent than those observed with tricyclic antidepressants. Sertraline may be used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD) and social anxiety disorder (social phobia). "
drugbank:interactsWith	drug:Tamsulosin
owl:sameAs	drug:Phenelzine
owl:sameAs	drug:Carvedilol
owl:sameAs	drug:Clozapine
owl:sameAs	drug:Pimozide
owl:sameAs	drug:Trimipramine
drugbank:interactsWith	drug:Ginkgo biloba
drugbank:interactsWith	drug:Trazodone
owl:sameAs	drug:Desvenlafaxine
drugbank:interactsWith	drug:Tamoxifen
drugbank:interactsWith	drug:Tiaprofenic acid
owl:sameAs	drug:Clarithromycin
owl:sameAs	drug:Moclobemide
drugbank:interactsWith	drug:Isocarboxazid
drugbank:interactsWith	drug:Moclobemide
owl:sameAs	drug:Ketoprofen

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 85 triples

Context graph