Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00943"

PredicateValue (sorted: default)
rdfs:label
"Zalcitabine"
rdf:type
drugbank:drugs
drugbank:description
"A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy. [PubChem]"
drugbank:drugCategory
drugcategory:Anti-HIV Agents
drugcategory:Antimetabolites
drugcategory:Reverse Transcriptase Inhibitors
drugbank:interactsWith
drug:Lamivudine
drug:Pentamidine
drug:Ribavirin
drug:Didanosine
owl:sameAs
drug:APRD00562
drug:Lamivudine
drug:Pentamidine
drug:Ribavirin
drug:Didanosine
drug:Zalcitabine

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 9 triples

Context graph