Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00745"

PredicateValue (sorted: default)
rdfs:label
"Modafinil"
rdf:type
drugbank:drugs
drugbank:description
"Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA."
drugbank:drugCategory
drugcategory:Appetite Depressants
drugcategory:Central Nervous System Stimulants
drugcategory:Neuroprotective Agents
drugcategory:Stimulants
drugbank:interactsWith
drug:Cyclosporine
drug:Clozapine
drug:Carisoprodol
drug:Voriconazole
drug:Trimipramine
drug:Triazolam
drug:Telithromycin
drug:Ethinyl Estradiol
drug:Mestranol
drug:Roflumilast
owl:sameAs
drug:APRD00534
drug:BE0002638
drug:Cyclosporine
drug:Clozapine
drug:Carisoprodol
drug:Voriconazole
drug:Trimipramine
drug:Modafinil
drug:Triazolam
drug:Telithromycin
drug:Ethinyl Estradiol
drug:Mestranol
drug:Roflumilast
drug:DBMET00378

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 21 triples

Context graph