Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00672"

Predicate	Value (sorted: none)
drugbank:interactsWith	drug:Sulfamerazine
drugbank:interactsWith	drug:Esmolol
owl:sameAs	drug:Carteolol
drugbank:interactsWith	drug:Sulfamethizole
owl:sameAs	drug:APRD00029
drugbank:interactsWith	drug:Bevantolol
owl:sameAs	drug:DBMET00201
owl:sameAs	drug:Sulfapyridine
owl:sameAs	drug:Sulfadiazine
drugbank:interactsWith	drug:Trisalicylate-choline
drugbank:interactsWith	drug:Salsalate
rdf:type	drugbank:drugs
drugbank:interactsWith	drug:Acetylsalicylic acid
drugbank:interactsWith	drug:Sulfasalazine
drugbank:interactsWith	drug:Practolol
drugbank:interactsWith	drug:Sulfadoxine
owl:sameAs	drug:BE0002793
drugbank:interactsWith	drug:Rifampicin
drugbank:drugCategory	drugcategory:Hypoglycemic Agents
owl:sameAs	drug:Carvedilol
drugbank:interactsWith	drug:Carteolol
drugbank:interactsWith	drug:Nadolol
owl:sameAs	drug:Acebutolol
owl:sameAs	drug:Nadolol
drugbank:interactsWith	drug:Penbutolol
drugbank:interactsWith	drug:Pindolol
owl:sameAs	drug:DBMET00199
drugbank:drugCategory	drugcategory:Antidiabetic Agents
drugbank:interactsWith	drug:Sulfamethoxazole
owl:sameAs	drug:Metoprolol
owl:sameAs	drug:Sulfamerazine
owl:sameAs	drug:Oxprenolol
rdfs:label	"Chlorpropamide"
owl:sameAs	drug:Penbutolol
drugbank:interactsWith	drug:Diazoxide
drugbank:interactsWith	drug:Voriconazole
owl:sameAs	drug:Trisalicylate-choline
owl:sameAs	drug:Sulfisoxazole
drugbank:interactsWith	drug:Labetalol
owl:sameAs	drug:Chlorpropamide
owl:sameAs	drug:Acetylsalicylic acid
drugbank:interactsWith	drug:Sotalol
owl:sameAs	drug:Phenylbutazone
owl:sameAs	drug:Practolol
drugbank:interactsWith	drug:Sulfacytine
drugbank:interactsWith	drug:Sulfamethazine
drugbank:interactsWith	drug:Somatropin recombinant
owl:sameAs	drug:Bisoprolol
owl:sameAs	drug:Sulfacytine
drugbank:interactsWith	drug:Carvedilol
owl:sameAs	drug:Betaxolol
drugbank:interactsWith	drug:Chloramphenicol
drugbank:description	"Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33). Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. Renal and hepatic dysfunction may increase the risk of hypoglycemia. "
drugbank:interactsWith	drug:Metoprolol
owl:sameAs	drug:Sotalol
owl:sameAs	drug:Propranolol
owl:sameAs	drug:Sulfamethoxazole
owl:sameAs	drug:DBMET00977
owl:sameAs	drug:Chloramphenicol
owl:sameAs	drug:DBMET00200
owl:sameAs	drug:Voriconazole
owl:sameAs	drug:Atenolol
owl:sameAs	drug:Esmolol
owl:sameAs	drug:Glucosamine
owl:sameAs	drug:Diazoxide
owl:sameAs	drug:Timolol
drugbank:interactsWith	drug:Glucosamine
owl:sameAs	drug:Rifampicin
drugbank:interactsWith	drug:Clofibrate
owl:sameAs	drug:Pindolol
drugbank:interactsWith	drug:Sulfisoxazole
owl:sameAs	drug:Sulfadoxine
drugbank:interactsWith	drug:Bisoprolol
drugbank:interactsWith	drug:Betaxolol
owl:sameAs	drug:Sulfasalazine
drugbank:interactsWith	drug:Sulfapyridine
drugbank:interactsWith	drug:Sulfadiazine
owl:sameAs	drug:Sulfamethizole
drugbank:interactsWith	drug:Dicoumarol
drugbank:interactsWith	drug:Phenylbutazone
owl:sameAs	drug:Bevantolol
owl:sameAs	drug:Labetalol
owl:sameAs	drug:Somatropin recombinant
drugbank:interactsWith	drug:Oxprenolol
owl:sameAs	drug:Clofibrate
owl:sameAs	drug:Sulfamethazine
owl:sameAs	drug:Salsalate
owl:sameAs	drug:Dicoumarol
drugbank:interactsWith	drug:Atenolol
drugbank:interactsWith	drug:Timolol
drugbank:interactsWith	drug:Propranolol
owl:sameAs	drug:BE0003536
drugbank:interactsWith	drug:Acebutolol

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 81 triples

Context graph