Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00612"

Predicate	Value (sorted: default)
rdfs:label	"Bisoprolol"
rdf:type	drugbank:drugs
drugbank:description	"Bisoprolol is a cardioselective &beta;1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the <i>para</i> position of the benzene ring. The &beta;1-selectivity of these agents is thought to be due in part to the large substituents in the <i>para</i> position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac &beta;1-adrenergic receptors with little activity against &beta;2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only <i>l</i>-bisoprolol exhibits significant &beta;-blocking activity."
drugbank:drugCategory	drugcategory:Adrenergic beta-1 Receptor Antagonists drugcategory:Antihypertensive Agents drugcategory:Sympatholytics
drugbank:interactsWith	drug:Insulin Lispro drug:Insulin Glargine drug:Pipobroman drug:Methysergide drug:Disopyramide drug:Lidocaine drug:Dihydroergotamine drug:Indomethacin drug:Treprostinil drug:Acetohexamide drug:Prazosin drug:Piroxicam drug:Clonidine drug:Voriconazole drug:Verapamil drug:Epinephrine drug:Chlorpropamide drug:Ergotamine drug:Orciprenaline drug:Tolazamide drug:Terbutaline drug:Repaglinide drug:Salmeterol drug:Telithromycin drug:Formoterol drug:Salbutamol drug:Glyburide drug:Rifampicin drug:Ibuprofen drug:Isoprenaline drug:Glipizide drug:Gliclazide drug:Tolbutamide drug:Terazosin drug:Ergonovine drug:Fenoterol drug:Glisoxepide drug:Pirbuterol drug:Insulin Aspart drug:Insulin Detemir drug:Insulin Glulisine drug:Procaterol drug:Glycodiazine drug:Indacaterol
owl:sameAs	drug:APRD00257 drug:Insulin Lispro drug:Insulin Glargine drug:Pipobroman drug:Methysergide drug:Disopyramide drug:Lidocaine drug:Dihydroergotamine drug:Indomethacin drug:Treprostinil drug:Acetohexamide drug:Prazosin drug:Piroxicam drug:Clonidine drug:Voriconazole drug:Bisoprolol drug:Verapamil drug:Epinephrine drug:Chlorpropamide drug:Ergotamine drug:Orciprenaline drug:Tolazamide drug:Terbutaline drug:Repaglinide drug:Salmeterol drug:Telithromycin drug:Formoterol drug:Salbutamol drug:Glyburide drug:Rifampicin drug:Ibuprofen drug:Isoprenaline drug:Glipizide drug:Gliclazide drug:Tolbutamide drug:Terazosin drug:Ergonovine drug:Fenoterol drug:Glisoxepide drug:Pirbuterol drug:Insulin Aspart drug:Insulin Detemir drug:Insulin Glulisine drug:Potassium drug:Procaterol drug:Calcium drug:Glycodiazine drug:Indacaterol drug:DBSALT001015

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 91 triples

Context graph