Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00495"

PredicateValue (sorted: default)
rdfs:label
"Zidovudine"
rdf:type
drugbank:drugs
drugbank:description
"A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. [PubChem]"
drugbank:drugCategory
drugcategory:Anti-HIV Agents
drugcategory:Antimetabolites
drugcategory:Reverse Transcriptase Inhibitors
drugbank:interactsWith
drug:Interferon beta-1b
drug:Methadone
drug:Rifabutin
drug:Stavudine
drug:Ribavirin
drug:Tipranavir
drug:Doxorubicin
drug:Ganciclovir
drug:Probenecid
drug:Rifampicin
drug:Atovaquone
drug:Rifapentine
drug:Clarithromycin
drug:Valganciclovir
owl:sameAs
drug:APRD00449
drug:Interferon beta-1b
drug:Methadone
drug:Zidovudine
drug:Rifabutin
drug:Stavudine
drug:Ribavirin
drug:Tipranavir
drug:Doxorubicin
drug:Ganciclovir
drug:Probenecid
drug:Rifampicin
drug:Atovaquone
drug:Rifapentine
drug:Clarithromycin
drug:Valganciclovir
drug:DBMET00718
drug:DBMET00720
drug:DBMET00721
drug:DBMET00756

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 29 triples

Context graph