Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00245"

PredicateValue (sorted: default)
rdfs:label
"Benzatropine"
rdf:type
drugbank:drugs
drugbank:description
"Benzotropine is a centrally-acting, antimuscarinic agent used as an adjunct in the treatment of Parkinson’s disease. It may also be used to treat extrapyramidal reactions, such as dystonia and Parkinsonism, caused by antipsychotics (e.g. phenothiazines). Symptoms of Parkinson’s disease and extrapyramidal reactions arise from decreases in dopaminergic activity which creates an imbalance between dopaminergic and cholinergic activity. Anticholinergic therapy is thought to aid in restoring this balance leading to relief of symptoms. In addition to its anticholinergic effects, benztropine also inhibits the reuptake of dopamine at nerve terminals via the dopamine transporter. Benzotropine also produces antagonistic effects at the histamine H1 receptor. "
drugbank:drugCategory
drugcategory:Antidyskinetics
drugcategory:Antiparkinson Agents
drugcategory:Dopamine Uptake Inhibitors
drugcategory:Muscarinic Antagonists
drugcategory:Parasympatholytics
drugbank:interactsWith
drug:Trospium
drug:Tacrine
drug:Triprolidine
drug:Haloperidol
drug:Trimethobenzamide
drug:Galantamine
drug:Donepezil
drug:Rivastigmine
owl:sameAs
drug:APRD00748
drug:Trospium
drug:Tacrine
drug:Triprolidine
drug:Haloperidol
drug:Trimethobenzamide
drug:Galantamine
drug:Donepezil
drug:Rivastigmine
drug:DBSALT000894

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 16 triples

Context graph