Local view for "http://wifo5-04.informatik.uni-mannheim.de/drugbank/resource/drugs/DB00203"

PredicateValue (sorted: default)
rdfs:label
"Sildenafil"
rdf:type
drugbank:drugs
drugbank:description
"Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH. "
drugbank:interactsWith
drug:Erythromycin
drug:Nelfinavir
drug:Indinavir
drug:Cimetidine
drug:Ciprofloxacin
drug:Voriconazole
drug:Amprenavir
drug:Nitroglycerin
drug:Conivaptan
drug:Isosorbide Dinitrate
drug:Tipranavir
drug:Telithromycin
drug:Isosorbide Mononitrate
drug:Ketoconazole
drug:Atazanavir
drug:Vigabatrin
drug:Terazosin
drug:Itraconazole
drug:Clarithromycin
drug:Fosamprenavir
drug:DB06154
drug:Asenapine
drug:Etravirine
owl:sameAs
drug:APRD00556
drug:BE0002363
drug:BE0002638
drug:BE0002793
drug:BE0003536
drug:Erythromycin
drug:Sildenafil
drug:Nelfinavir
drug:Indinavir
drug:Cimetidine
drug:Ciprofloxacin
drug:Voriconazole
drug:Amprenavir
drug:Nitroglycerin
drug:Conivaptan
drug:Isosorbide Dinitrate
drug:Tipranavir
drug:Telithromycin
drug:Isosorbide Mononitrate
drug:Ketoconazole
drug:Atazanavir
drug:Vigabatrin
drug:Terazosin
drug:Itraconazole
drug:Clarithromycin
drug:Fosamprenavir
drug:DB06154
drug:Asenapine
drug:Etravirine
drug:DBMET00182
drug:DBSALT000347

All properties reside in the graph file:///home/swish/src/ClioPatria/guidelines3/drugbank_small.nt

The resource appears as object in 46 triples

Context graph